Potential Cell Lines

http://research.jax.org/grs/alzheimers.html

Mouse models commonly used

Trans-genes and knockouts.

http://www.sciencedirect.com.ezproxyberklee.flo.org/science/article/pii/S0925443911002754

senescence accelerated mice (SAM) used to model aging and Alzheimer's related neuronal damage.

SAMP8 can model oxidative stress and onset of Alzheimer's.

http://www.sciencedirect.com.ezproxyberklee.flo.org/science/article/pii/S0022510X13030888

Exposure of  SAMP8 and SAMP10 hippocampal neurons to oxidative stress induces changes in miRNA expression levels corresponding to those of Alzheimer's.

miR-329, miR-193b, miR-20a, miR-296, and miR-130b were upregulated in response to exposure to H₂O₂.

Full paper unavailable.