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http://www.ncbi.nlm.nih.gov/pubmed/24858274

 

MicroRNA1Alzheimer Disease Affected TissueAging ModelReference
CortexHippocampusCerebellumCSFPBMC
Down-Regulated 
let-7i↓    ↓[96,169]
miR-9↓↓↓   [99, 96]
miR-15↓  ↓  [99, 96]
miR-146b↓↓↓↓  [99]
miR-181c↓  ↓  [99, 96]
miR-210↓↓    [99, 96]
miR-338↓  ↓  [99, 96]
miR-451   ↓ ↓[99, 169]
Up-Regulated 
let-7f   ↑↑↑[99, 39, 181]
miR-30d   ↑ ↑[99, 169]
miR-34a↑↑↑ ↑↑[39, 99, 169, 170]
miR-125b↑↑↑   [99, 98]
miR-197↑  ↑  [99, 96]
miR-200a↑   ↑ [99, 39]
miR-371   ↑↑ [99, 39]
miR-517   ↑↑↑[99, 39]
miR-520h↑   ↑ [96, 39]

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705849/

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705849/

http://genomebiology.com/2013/14/7/R78

 

 

Order?R
-34aU
-146aU
let-7fU
-9D
-146aD
-181cD
-106a/bD
-107D
-29a/bD
  

Up-Regulated

Down-Regulated

brain-miR-112

hsa-miR-107

brain-miR-161

hsa-miR-103a-3p

hsa-miR-26a-5p

hsa-miR1-532-5p

hsa-miR-5010-3p

hsa-miR-26b-5p

hsa-miR-1285-5p

hsa-let-7f-5p

hsa-miR-151a-3p

 

hsa-let-7d-3p

 
  1. miR 34-a Brain Tumor + Alzheimer's
  2. miR 146-a: thyroid cancer and arthritis + Alzheimer's

 

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