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CHO (Chinese Hamster Ovaries)
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http://research.jax.org/grs/alzheimers.html
Mouse models commonly used
Trans-genes and knockouts.
http://www.sciencedirect.com.ezproxyberklee.flo.org/science/article/pii/S0925443911002754
senescence accelerated mice (SAM) used to model aging and Alzheimer's related neuronal damage.
SAMP8 can model oxidative stress and onset of Alzheimer's.
http://www.sciencedirect.com.ezproxyberklee.flo.org/science/article/pii/S0022510X13030888
Exposure of SAMP8 and SAMP10 hippocampal neurons to oxidative stress induces changes in miRNA expression levels corresponding to those of Alzheimer's.
miR-329, miR-193b, miR-20a, miR-296, and miR-130b were upregulated in response to exposure to H2O2.
Full paper unavailable.