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  • Parts list - look at last year's method of sorting
    • Put plasmids on to that list  

Plasmid Progress: on Parts List by 3pm

  • miRNA:
    • meeting with Jeremy about plasmids for high and low sensors 
  • Treatment: 
    • waiting BACE2 + primers 
    • looking into BACE1 plasmids (pENTR and miRNA) 
    • TRE + BACE2 plasmid 
    • BACE2-YFP pENTR (C terminal fusion designed, N terminal fusion should be easy to design)
    • Notes 
      • intronic w/ mKate
      • U6 promoter 
      • U6 teto promoter regulated with tetR 
  • Antibodies: 
    • Gantenerumab (Gmab): we have heavy and light chain gBlocks 
    • CD79A/B: we have pENTR 
    • Reporter circuit: we have from Valia 
    • Lyn: we have pENTR
      • Look into point mutating it for autophosphorylation
      • EYFP fusion
    • Syk: we have pENTR
      • look into point mutating it 
      • fusion with EYFP and TEVp 
    • TEV related plasmids that we have (talk to Nevin): 
      •  Gal4UAS-EYFP
      • Gal4UAS-mKate
      • TRE-TEVp
      • Hef1a-rtTa
      • TRE-Syk-TEVp
      • TRE-EBFP-TEVp
    • G-mab heavy chain - Tcs - Gal4VP16 fusion being designed 
    • CD79A/B - Tcs - Gal4VP16 being designed
  • Receptors:
    • Have: pENTR: LilrB2, PirB, Hef1a
    • Designed: LilrB2/PirB-EBFP