How To Please Ron/Brain

miRNA Sensors (Theory)

  • Obtain pEXPR: hEF1a-GAL4VP16
  • Fill out the Genewiz Order Form to sequence Low Sensor miR-144
  • Prepare transfection well plate maps
  • So where are the siRNA though...
  • Why didn't the GH golden gate work on try #3?
  • Change name of high sensors in tree

miRNA Sensors (Lab Work)

  • Pick colonies
    • pEXPR: TAL14-mKate
  • Midiprep
    • pEXPR: MAV1212-Hef11a-eBFP2
    • Mutant Hef1a-2xKturn-eGFP
    • Wild Type Hef1a-2xKturn-eGFP
    • Low Sensor miR-144
    • Hef1a-L7ae (LR)
  • Miniprep
    • MAV1212-mRFP
    • L1_TALER14_L2
    • pTAL14-mKate-pEST
  • LR
    • pEXPR: MAV1212-TRE-L7ae

NOTES

so...the siRNA are nowhere to be found

hEF1a-TAL14 (LR) has no colonies

TRE is nowhere to be found

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