How To Please Ron/Brain

miRNA Sensors (Theory)

  • Troubleshoot
    • What's going on with the double input low sensor
  • Move siRNA into our cryobox

miRNA Sensors (Lab Work)

  • Pick colonies
    • High Sensor miR-30d
    • High Sensor miR-146a
    • High Sensor let-7f
    • High Sensor miR-125b
    • Low Sensor miR-144
    • Low Sensor miR-181c
    • pENTR: TAL14
    • pENTR: TAL21
    • pENTR: Something for yeast for Brian
  • Restriction Digest & run gel
    • pEXPR: MAV1212-TRE-L7ae (LR)
    • pEXPR: MAV1212-hEF1a-GAL4VP16 (LR)
    • pEXPR: MAV1212-TRE-GAL4VP16 (LR)
  • Inoculate midiprep culture?
    • If the LR's have the right sequence
  • Transform
    • Re transform MAV1212-hEF1a-TAL14 LR
  • FACS Prep

NOTES

The digest keeps failing

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