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How To Please Ron/Brain

  •  AD blood cells from PrecisionMed? Talk to Brian?
  •  Meet with Kyle about designing siRNA (email sent)
    •  Make siRNA sequences in geneious
    •  Send order to Brian
  •  Picture of how low sensors come together

...

miRNA Sensors (Theory)

  •  Determine which pairs of target sites we want
    •  Find sequences (hopefully under 200 bp)
    •  Send ultramer order to Brian
  •  Plan new MAV vector
  •  Plan high sensor construction (meet with Brian)

...

miRNA Sensors (Lab Work)

  •  Golden Gate
    •  Gather miRNA target sites from Jeremy
      •  Nanodrop for concentrations ( ? )
    •  Make all 6 single low sensors (in conjunction with antibody group)
  •  Miniprep eBFP2

...

NOTES

Both LR's failed (mKate2 and L7ae)

Meeting w/ Jeremy tomorrow to talk about new MAV vector and high sensors

We need to Gibson in  eBFP2 before we can finish the sensors