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  • Normally brewed overnight
    • Regular cold brew is normally steeped for 10-12 hours 
  • Can be brewed faster under higher pressure
    • Pressure of compression will be tested
    • Use a french press/aeropress method to compress the grounds
      • Pressure of compression will be tested
    • Will be brewed during launch and using room temperature water
  • Will have a control group that will be brewed using regular cold brew methods on the ground
  • Grounds
    • Coarse
    • Will be bought pre-grounded (from whatever company sponsors us)

...

Possible Development of a cold brew design?


10/10/24

Spine:

  • Materials:
    • Model section of spine (focus on vertebrae or discs?)
      • Upper spine (neck area) - feels the most force because head is heavy - part of the spine that becomes weakest in older adults
      • Lower spine - for someone with a medical condition
      • Model section of spine (focus on vertebrae or discs?)
      • Brace (non-invasive)
      • Extra: skin like material to see how much damage the brace would do
      Finding a good fake bone material
    • Challenges:
    • How will the brace enact force on the test spine
      • Spine has bone and ligament sections. Do we also need to model the squishy ligament sections for this to be accurate? I feel like the squishy ligament sections would respond most to compression (more squishy than bone) so maybe idk
      • How to brace non-invasively inside the payload?will the brace enact force on the test spine
      • Finding a good fake bone material
      • How to brace non-invasively inside the payload?
      • What are we measuring? How will we collected data? - displacement, something to measure forces between vertebrae?
      • Do we need to simulate weight of the head? - scale down the spine and just add weights on top
    • Plan:
      • Do we want multiple brace designs
      • At least one braced ‘spine’ and one control
      • Do we want multiple brace designs
      • Create brace similar to traditional medical brace
      • Angled spine to be more realistic to how astronauts actually sit in rocket

    ...

    • Individuals in air travel have often been reported to experience hypoglycemia (too much insulin is delivered by the pump during takeoff?)
    • Materials 
      • Insulin/IV drip
        • Force comes from gravitational pull, so the drip bag must be kept higher than the place insulin/IV fluid is delivered
      • Mechanical IV/ insulin pump 
        • Functions like a syringe
        • Doesn’t function based on gravity, will it still be impacted by the increased g forces?
      • Delivery site 
        • Synthetic model of human fatty tissue?
        • Insulin/IV drip
        • Mechanical IV/ insulin pump 
      • Challenges
      • What are we measuring?
        • Delivery site 
      • Challenges
        • Flow rate through a small tube? Fluid delivered somewhere?
        • Goal to maintain a constant flow rate (drip rate) throughout flight?
        • What are we measuring?


      10/13/2024

      asdf

      We did a intense brainstorm and design session for the updated payload project. We decided on the neck brace, and conducted research on different elements of the project. 

      ...

      https://www-sciencedirect-com.ezproxyberklee.flo.org/topics/medicine-and-dentistry/cervical-collar

      ...

      • Force Capacity = 50 kN/11250 lbf 
        • Is this limit going to affect the accuracy of our measurements of the stress/strain imposed on the spinal structure? 
        • Note that the forces we will be loading onto the apparatus likely don’t need 50 kN to simulate the maximum load case adequately.
          • Is this limit going to affect the accuracy of our measurements of the stress/strain imposed on the spinal structure? 
      • Min. speed = 0.001 mm/min
      • Min. speed = 0.001 mm/min
      • Max. speed = 762 mm/min 
      • Max force at full speed = 25 kN/5620 lbf
      • Position Control Resolution = 1.8 nm
        • Able to provide a relatively accurate amount of force onto the entire spine, which we still have to determine.
        • Specs
          • Note that we have:
          • Which is the maximum space we will have to accommodate the entire apparatus ( given we’re going to be ditching the CubeSat design because of the want to replicate the 75-degree angled decline, we’d have to design some accommodation for this simulation that can fit not only within the 
          • Able to provide a relatively accurate amount of force onto the entire spine, which we still have to determine.
          • Specs

        Procedure:

        1. Enable the machine and for legacy machines you have to wait for the self-test to run on the device, allowing for software to run.
        2. Tools:
          1. Buttons: able to perform big movements of the crosshead
          2. Thumbwheel: for more precise movements of the crosshead 
          1. Red Button ( able to Red Button ( able to stop unexpected movements of the crosshead )
          2. Spring Device ( used to mitigate the effect of unexpected movements of the crosshead ) 
          3. Remote 
          4. Buttons: able to perform big movements of the crosshead
          5. Thumbwheel: for more precise movements of the crosshead 
        3. Calibrate the device every 8-12 hours 
        4. Grips ( depending on how big the apparatus is, we’d have to design for this ) 
          1. It’s the same idea for holding for the limits on the grip ( we’d have to attach an air hose to actuate the grips on the apparatus 
        5. Use the specimen aligning device to help with aligning the apparatus onto the grips
        6. Move the limit switches according to the movement to prevent collision of the crosshead to the lower base of the grips 

        ...

        1. What needs to fit?
          1. At least two simulated spines with weights (simulating head weight) and braces attached, along with all sensors. 
        2. How much space do we have to work with?
          1. 10 cm x 30cm
        3. What weight do we have to work with?
          1. 8.8 lbs
          2. 2.25 lbs of boiler plate mass
        4. How do we attach the “fake spines” to the structure?
          1. Option 1: 3D print stabilizers to attach to the top/bottom which attach to the frame. 
          2. Option 2: Connect with some form of glue/epoxy/resin to the frame directly. 
        5. If the spine(s) is “angled”, how do we minimize wasted space?
        6. Not much space for an angled spine
          1. At 0 degree angle, length < 30 cm
          2. Maximum angle from vertical can be 19.84° - length < 31.62 cm
          3. Usual angle from vertical is 75-85°
            1. Spine length < 10.35 - 10.03 (basically 10 cm)
          1. Not much space for an angled spine
        7. What sensors are going to be as a part of payload, and where do they need to be (relative to the spine)?
          1. If the spine is placed vertically, sensors can be arranged around the spine, and at the base. They can also be attached directly to the spine/brace. 
          2. If the spine is horizontal, there is room for either more sensors or more spines. 
        8. What weight is going to be on top of the spine? 
          1. Depending on how scaled down the spines are, the weight will vary (see section 8)
        9. What scale are we using?
          1. A human spine has an approximate length of 71cm (male) to 61cm (female) in the neck region (first seven vertebrae, C1-C7)
          2. If the simulated spines are approximately 30cm in length, the simulated head should be around 3.1 lbs (assuming average head weight is 7.5lbs). 
          3. If the simulated spines are approximately 10cm in length, the simulated head should be around 1.05 lbs (assuming average head weight is 7.5lbs).

        ...

        • 3D Printed Spine ✅
        • Neck mold
        • Springs?
          • Alternatives:
            • Foam
            • Silicon or silicon gel
            • Alternatives:



          Concerns:

          • Putting the vertebrae inside of a liquid gel mold that will then solidify will fill every crevice of the neck vertebrates and COULD prevent the compression 
          • Choosing the right material for modeling intervertebral discs 

          ...

          • Design Requirements:
          • The highest temperature experienced is going to be the exterior temperature of the environment which is 100 F 
          • We want extremely small tolerances so minimal changes during the manufacturing process 


          Material 

          Cons

          Pros

          Dragon Skin 10 (Needs a degassing process to remove excess bubbles, have to see if we have a vacuum chamber, and this may apply to other materials)

          • Tensile Strength: 475 psi

          Have to create subtractive molds for the portion between the bones that are almost completely accurate

          Shrinkage is possible, depending on the conditions



          Superb service range temperatures ( -65°F to +450°F or -53°C to +232°C ) 

          Molds are reusable so its easy to create multiple

          Skrinkage, though possible, is minimized ( <.001 in. / in. ) 

          Soft Flexi Foam

          Has no resistance to compression 

          Have to manufacture the soft flexi foam so it accurately reflects the disks

          Easy to conform to the vertebrae because of its “foamy” nature 

          Silicon - What kind of silicon are we using? I think Dragonskin is also a derivative of silicon



          Ecoflex 00-50 

          • Tensile Strength: 315 psi 
          • EcoFlex 00-10 
            • Tensile Strength: 120 psi 

          Should be Ecoflex 10 or 20 ( available on the website ) if it wants to simulate human tissue

          Basically has the same pros/cons as Dragon Skin 10, with the curing process and temperature range 

          Able to simulate the compression of the disks as it retains its shape following compression 


          Ballistic Gel

          Maybe we can do a combination of Ballistic gel with some other material to simulate the spine

          Impact forces

          Environmental temperatures, the shelf-stable temperature  is -10OF - 95 O





          Certified because of extensive use in the medical industry

          Medical-grade plastic (polyethylene)





          Shopping List Materials:

          Material

          Price per unit

          Quantity (# units)

          Purpose

          SimuBone Filament Roll

          https://www.3dxtech.com/products/simubone-r

          $98

          1

          3d printing material for vertebrae - each set of vertebrae uses 20 grams of material (1 spool comes with 750 grams)

          FlexiForce A201 Sensor (8 Pack)

          https://www.tekscan.com/products-solutions/force-sensors/a201

          $153

          1

          Measure the compression forces on the spine. 

          Raspberry Pi Zero

          Amazon.com: Raspberry Pi Zero W with Vilros Adapters & Quickstart E-Book Download Code-includes USB OTG Adapter, HDMI Adapter, Camera Module Adapter, 40 Pin Header, Heatsink & Vilros Pi Zero Quickstart Ebook : Electronics

          $25

          1

          Breadboard with an MPC3008 integrated circuit converts analog signals from force sensors into digital signals that can be read by Raspberry Pi Zero. Raspberry Pi Zero retrieves the data. 

          3.7v 18650 cylindrical lithium-ion batteries

          (2 Pack)

          Amazon.com: FORCETEKDATA 2 Pack 3.7v 2200mAh ICR18650 Rechargeable Lithium Ion Battery with SM 2P Plug : Health & Household

          $19.95

          1

          Powers the system. 



          Questions To Ask

          1. We are members of the MIT rocket team. We are launching a rocket with the purpose of simulating the effects of the g-forces on the cervical spine with and without a neck brace of our own design. We wanted your expertise to choose the materials for our spine model. Specifically, which material would be best for the intervertebral discs and a “container” to hold the model representing the human neck. 

          ...

          • Putting the vertebrae inside of a liquid gel mold that will then solidify will fill every crevice of the neck vertebrates and COULD prevent the compression 
          • Choosing the right material for modeling intervertebral discs 


          November 10, 2024

          Young’s modulus of intervertebral disk: 30 MPa in the linear elastic regime (that’s actually really high)

          Words when presenting: ultimate strength and young’s modulus 

          Possible Links: 


          Here is a type of polyurethane foam with roughly the correct density that gives a Young’s modulus in the 10-30 MPa range: https://makerstock.com/collections/foam/products/cnc-and-modeling-foam-rigid-polyurethane-foam-high-density-8lb-ft3

          Material

          Young Modulus (basically how much it deforms under stress)

          Stress-Strain Curve

          Ultimate Strength

          Intervertebral Disk

          30 MPA / 0.03 GPa



          Rubber (Small Strain)

          10-100 MPa



          Silicone Rubber

          0.517-62.1 MPa


          0.138 - 165 MPa (tensile strength, ultimate)

          LDPE

          150-520 MPa


          10.3-18 MPa (tensile strength, ultimate)

          Polyethylene 




          UHMW Polyethylene (used in actual disc replacements)

          760 MPa



          Polyurethane Rubber

          6 MPa


          25 MPa

          EVA (Ethylene Vinyl Acetate)

          (this is what shoe soles are made of!)

          10-200 MPa? 7-120 MPa? 15-80 MPa

          Pure EVA, 0.3 wt%, 2 wt% stress-strain curve, Young’s modulus, elongation


          0.16g/cm^3 polyurethane foam

          15 MPa



          Memory Foam (a type of polyurethane foam)








          Notes for substitute intervertebral disc material:

          Lumbar spine stress-strain curves?

          From this article: “Stress–strain characteristic curve of the intervertebral disc at different strain rates. Both the yielding and cracking phenomenon occur at fast and medium loading rates, while only the yielding phenomenon occurs at slow loading rates. (A) The mechanical behavior in L1–2 Segment; (B) The mechanical behavior in L3–4 Segment; (C) The mechanical behavior in L5–6 Segment.”

          Note: Material for head weight

          Material

          Height

          Density

          Radius

          Outer Diameter 

          Shape

          Weight (not accounting for hole)

          Price

          Brass


          0.303 to 0.315 lb/in^3

          1.5


          Cylinder 

          3 lb 


          Stainless Stain 

          1.48 in. 

          0.27 to 0.29 lb/in^3

          1.5 in.

          3 in.

          Cylinder

          3lb

          $86.70 for 6 in

          Low-Carbon Steel







          $70 for 6 in


          Vertebrae 

          https://www.thingiverse.com/thing:4801717

          Proportion Head to Vertebrae:

          Piece

          Real Human

          Prototype

          Head Weight

          10 lbs

          3 lbs

          Vertebrae Weight 

          44.1 grams







          Head Weight

          Vertebrae Weight

          Real Human

          10 lbs

          44.1 grams 

          Prototype 

          3 lbs

          20 grams 


          Determination of Proportion:

          50% scale for the vertebrae, 30% scale for the head (maximum size for each permissible by dimensions of payload)