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- Gmab H
- Gmab L
- Syk-TEV
- Lyn-TEV
- Lyn
- CD79A
- CD79B
- CD79A-TCS-G4
- CD79B-TCS-G4
- UAS: mKate
- hEF1a: BFP
- abeta
- hEF1a: G4
Procedure:
| HEK control | BCR 100 Lyn 100 Syk 100 U:mKate 100 H:Gal4 100 | BCR 100 Lyn 100 Syk 100 U:mKate 100
| |||||||||
| HEK | Positive Control | Negative Control | |||||||||
| Syk => | |||||||||||
| Lyn => | |||||||||||
BCR-G4 100 h:eBFP 100 h:rtTA 100 H:Lyn 100 T:Syk-TEV 100 U:mKate 100 10 nM dox aIgM | BCR-G4 25 h:eBFP 100 h:rtTA 100 H:Lyn 100 T:Syk-TEV 100 U:mKate 100 10 nM dox aIgM | BCR-G4 6.25 h:eBFP 100 h:rtTA 100 H:Lyn 100 T:Syk-TEV 100 U:mKate 100 10 nM dox aIgM | BCR-G4 100 h:eBFP 100 h:rtTA 100 H:Lyn 100 T:Syk-TEV 100 U:mKate 100 10 nM dox | BCR-G4 25 h:eBFP 100 h:rtTA 100 H:Lyn 100 T:Syk-TEV 100 U:mKate 100 10 nM dox | BCR-G4 6.25 h:eBFP 100 h:rtTA 100 H:Lyn 100 T:Syk-TEV 100 U:mKate 100 10 nM dox | ||||||
BCR-G4 100 h:eBFP 100 h:rtTA 100 T:Lyn-TEV 100 U:mKate 100 10 nM dox aIgM | BCR-G4 25 h:eBFP 100 h:rtTA 100 T:Lyn-TEV 100 U:mKate 100 10 nM dox aIgM | BCR-G4 6.25 h:eBFP 100 h:rtTA 100 T:Lyn-TEV 100 U:mKate 100 10 nM dox aIgM | BCR-G4 100 h:eBFP 100 h:rtTA 100 T:Lyn-TEV 100 U:mKate 100 10 nM dox | BCR-G4 25 h:eBFP 100 h:rtTA 100 T:Lyn-TEV 100 U:mKate 100 10 nM dox | BCR-G4 6.25 h:eBFP 100 h:rtTA 100 T:Lyn-TEV 100 U:mKate 100 10 nM dox | ||||||
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Results:
Discussion:
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